Firearm ocular injury is a general term for trauma to the globe, ocular adnexa, and orbit caused by firearms. In addition to mechanical trauma, chemical and thermal injuries from gunpowder residue combine, resulting in a more complex pathology than blunt trauma.
In the United States, an estimated 3.15 ocular injuries per 1,000 population are treated in emergency departments annually. One-third of patients with severe ocular injuries do not recover vision to 20/200 or better. Analysis of the National Trauma Data Bank from 2008–2014 identified 8,715 (3.7%) ocular injuries among 235,254 patients presenting with firearm-related injuries 1. Of these, 1,972 (23%) were in children, most with risk of blindness and associated traumatic brain injury (TBI) 2.
Injury types are classified into the following three categories:
Open wounds of the globe or ocular adnexa: Trauma involving full-thickness defects of the cornea or sclera.
Orbital injury or orbital fracture: Trauma involving fracture of the orbital walls or intraorbital hemorrhage.
Contusion of the globe or adnexa: Blunt trauma with preserved integrity of the ocular wall but internal injury.
QIn which age group is ocular trauma from firearms most common?
A
The nature of risk varies by age. Children aged 0–3 years often sustain accidental injuries at home, and those under 10 years have a high risk of open globe injury. Individuals aged 19–21 years frequently sustain injuries on the street due to assault. The in-hospital mortality rate for children is reported to be 12.2%.
The Zone classification of open globe injury (OGI) is shown below. The more posterior the extent of injury, the worse the prognosis.
Zone
Injury site
Zone I
Cornea / limbus
Zone II
Up to 5 mm posterior to the limbus
Zone III
More than 5 mm posterior to the limbus (IIIb: posterior to the equator)
The breakdown of injury types in pediatric firearm-related ocular trauma (2008–2014) was: open globe injury 41.6%, orbital injury or fracture 30.0%, open wound of ocular adnexa 25.5%, and contusion of eye or adnexa 21.1% 2.
The types of firearms causing ocular trauma are diverse, including handguns, rifles, as well as airsoft guns and pellet guns, which can also cause severe eye injuries 3. Injuries may combine mechanical trauma, chemical trauma (from gunpowder residue), and thermal trauma.
Age-specific risk factors are shown below.
Age group
Main risk factors
Odds ratio
0–3 years
Unintentional injury (at home)
OR 4.41 (home: OR 5.39)
Under 10 years
Open globe injury (OGI)
OR 1.84
19–21 years
Assault (on street)
OR 2.17 (street: OR 1.61)
QCan airsoft guns cause serious eye injuries?
A
Severe eye injuries such as hyphema, traumatic mydriasis, and retinal hemorrhage from airsoft gun pellets have been reported 4. In a US pediatric case analysis, about 28% of injured patients had visual acuity less than 20/50 after initial treatment, and over 98% of cases were not wearing protective eyewear. Proper protective eyewear is essential when using firearms, including airsoft guns.
Even if anterior segment findings are normal, CT examination should be performed if there is a history of trauma to prevent oversight. Pay attention to subtle signs such as subconjunctival hemorrhage, edema, and foreign body entry sites.
CT can simultaneously evaluate not only the location and size of intraocular and orbital foreign bodies but also intracranial changes. When globe rupture is suspected, do not press the probe firmly during ultrasound.
QCan MRI be performed when ocular trauma from firearms is suspected?
A
MRI is contraindicated if a metallic foreign body is suspected. CT is the first-choice imaging modality, allowing simultaneous evaluation of intracranial changes and orbital/intraocular foreign bodies. MRI can only be performed if the foreign body is clearly non-magnetic.
If infection risk is high or surgical intervention is delayed: start with vancomycin + ceftazidime intravenously, then switch to oral ciprofloxacin or moxifloxacin after 1–2 days for a total of 7 days.
Symptomatic therapy includes antiemetics (ondansetron IV) to reduce intraocular pressure elevation and risk of intraocular content extrusion from Valsalva maneuver. For pain, morphine IV and sedatives are used.
Antifungal prophylaxis is not given unless there is evidence of fungal infection. Antibiotic prophylaxis for non-surgical orbital fractures in adults is also not recommended.
Primary surgery (wound closure) is recommended within 12–24 hours. The goal is infection prevention and avoidance of intraocular content extrusion.
Corneal wounds are closed with watertight sutures using 10-0 nylon, and scleral wounds with 7-0 nylon.
Small wounds localized anterior to the corneal rectus muscle insertion can be managed under local anesthesia.
If wound identification is difficult due to bleeding or edema, general anesthesia is selected.
Secondary surgery (lensectomy, vitrectomy) is generally performed as a second-stage procedure after primary surgery, but may be performed in a single stage if conditions permit. In cases of severe vitreous hemorrhage precluding fundus visualization, 3-port vitrectomy for removal of opaque vitreous and gas or silicone oil tamponade is performed.
If globe preservation is difficult, primary evisceration or enucleation is performed 5.
Intraocular foreign bodies should be removed as promptly as possible. The time to removal affects visual prognosis. Currently, removal is mainly performed via vitreous surgery (pars plana vitrectomy, PPV).
Anterior chamber, angle, iris foreign bodies: Removed with forceps through a corneoscleral incision with anterior chamber maintenance using viscoelastic material.
Vitreoretinal foreign bodies: Removed using vitreous surgery with intraocular magnets, microforceps, or diamond forceps.
Emergency surgery is required when extraocular muscle entrapment is present. In children with the triad of “orbital fracture, vomiting, and nausea,” the positive predictive value for entrapment is over 80%.
Non-urgent orbital fractures can be delayed for 7–14 days, and some cases do not require surgery.
Early ophthalmology consultation is important; a 2023 study reported survival rates of 92.3% when ophthalmology was involved in orbital fracture patients versus 43.8% when not involved.
QIs surgery always necessary for orbital fractures?
A
If extraocular muscle entrapment is present, emergency surgery is required. For non-urgent fractures, surgery can be considered after 7–14 days of observation, and some cases do not require surgery. In children, entrapment can be suspected with high probability based on the triad of orbital fracture, vomiting, and nausea.
Outcome: Can lead to severe visual impairment. Indication for secondary surgery (vitrectomy).
Post-traumatic endophthalmitis occurs in 2–7% of open globe injuries. Contamination from plants or soil leads to a high rate of blindness. Endophthalmitis caused by virulent bacteria such as Bacillus species is known. In the Zone classification, the more the injury extends to Zone III, the worse the visual prognosis.
7. Latest Research and Future Perspectives (Investigational Reports)
The United States Eye Injury Registry (USEIR) ceased operations in 2013, and the National Trauma Data Bank stopped collecting firearm-related data in 2014. This has resulted in a significant lack of population-based data on firearm-related eye injuries. Reconstruction of a comprehensive ocular trauma registry has been identified as a public health challenge.
Hospital-based violence intervention programs (HVIP) are gaining attention. The longest-running HVIP reported a 60% reduction in criminal activity among participating patients. Community/hospital-based programs (CVIP/HVIP), gun buyback events, and firearm safety courses are implemented in combination.
Waiting periods and child-access prevention laws are evaluated as effective policies supported by sufficient data. Modeling studies have also reported that promoting safe storage can prevent up to 32% of firearm-related deaths in the home. The American Medical Association (AMA) has expressed support for strengthening policies and research to improve firearm safety.
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Weiss R, He C, Gise R, Parsikia A, Mbekeani JN. Patterns of Pediatric Firearm-Related Ocular Trauma in the United States. JAMA Ophthalmol. 2019;137(12):1363-1370. doi:10.1001/jamaophthalmol.2019.3562. PMID: 31600369. PubMed↩↩2
Erickson BP, Feng PW, Ko MJ, Modi YS, Johnson TE. Gun-related eye injuries: A primer. Surv Ophthalmol. 2020;65(1):67-78. doi:10.1016/j.survophthal.2019.06.003. PMID: 31229522. PubMed↩
Lee R, Fredrick D. Pediatric eye injuries due to nonpowder guns in the United States, 2002-2012. J AAPOS. 2015;19(2):163-168.e1. doi:10.1016/j.jaapos.2015.01.010. PMID: 25818283. PubMed↩
Ben Simon GJ, Moisseiev J, Rosen N, Alhalel A. Gunshot wound to the eye and orbit: a descriptive case series and literature review. J Trauma. 2011;71(3):771-778. doi:10.1097/TA.0b013e3182255315. PMID: 21909007. PubMed↩
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