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16 English articles

Gelatinous Drop-like Corneal Dystrophy (GDLD)
Cornea & External Eye

Gelatinous drop-like corneal dystrophy (GDLD) is an autosomal recessive hereditary corneal disease caused by TACSTD2 gene mutations, leading to tight junction dysfunction and amyloid deposition beneath the corneal epithelium. It is relatively common in Japan and was designated as a specified intractable disease in 2019.

Ghost Cell Glaucoma
Glaucoma

Ghost cell glaucoma is a secondary open-angle glaucoma caused by obstruction of the trabecular meshwork by degenerated red blood cells (ghost cells) after vitreous hemorrhage, and most cases resolve with appropriate treatment.

Giant Papillary Conjunctivitis
Cornea & External Eye

Giant papillary conjunctivitis (GPC) is a conjunctivitis characterized by the formation of giant papillae (≥1 mm in diameter) on the upper tarsal conjunctiva due to mechanical irritation from contact lenses, ocular prostheses, surgical sutures, etc. It is classified as an independent disease type in the Japanese Guidelines for Allergic Conjunctival Diseases (3rd edition) and is most commonly seen in contact lens wearers.

Glaucoma after Corneal Transplantation
Glaucoma

This article explains the definition, incidence by surgical type, difficulties in intraocular pressure measurement, precautions for drug therapy, and stepwise treatment strategies including tube shunt surgery for secondary glaucoma occurring after corneal transplantation (PKP, DSAEK, DMEK).

Glaucoma Drainage Device (Tube Shunt Surgery)
Glaucoma

A glaucoma drainage device (GDD) is an implant consisting of a tube and a plate, and is a surgical option for refractory glaucoma when trabeculectomy is difficult. This article explains the domestically approved devices (Baerveldt® and Ahmed®), surgical techniques, evidence from TVT/PTVT studies, and pediatric indications.

Glaucoma in Eyes with Intraocular Lens Implantation or Aphakia (Post-cataract Surgery Glaucoma)
Glaucoma

This article explains the etiology, diagnosis, and treatment of pseudophakic glaucoma and aphakic glaucoma that occur after cataract surgery. It covers various mechanisms of intraocular pressure elevation, including retained ophthalmic viscosurgical devices (OVD), steroid-induced glaucoma, UGH syndrome, iris chafing, lens particles, pupillary block, and pigment dispersion. It details pharmacotherapy, including contraindications for Eybelis, and surgical indications.

Glaucoma Screening
Glaucoma

Glaucoma screening is a testing program to detect glaucoma early at an asymptomatic stage and prevent irreversible vision loss. Although mass screening of the general population is not recommended, targeted screening for high-risk groups is useful.

Glaucoma Secondary to Uveitis
Glaucoma

This article explains the pathology, diagnosis, and treatment of secondary glaucoma associated with uveitis. Intraocular pressure rises due to combined mechanisms of open-angle and angle-closure, leading to glaucomatous optic neuropathy.

Goldmann Applanation Tonometry
Other Eye Conditions

This article explains the Imbert-Fick principle of the Goldmann applanation tonometer (GAT), the gold standard for intraocular pressure measurement, detailed procedures including fluorescein staining and reading of semicircular images, the influence of central corneal thickness, setting and management of target intraocular pressure, and infection control.

Goldmann Kinetic Perimetry (GP)
Other Eye Conditions

This article explains the principles of Goldmann kinetic perimetry (GP), types of targets, examination techniques, interpretation of isopters, and typical visual field abnormality patterns (hemianopia, concentric constriction, ring scotoma). It is a useful examination method for full-field evaluation in advanced glaucoma, retinitis pigmentosa, and neuro-ophthalmic diseases.

Goniopuncture
Glaucoma

Indications, technique, and complications of Nd:YAG laser goniopuncture. Detailed description of the perforation procedure of the trabecular meshwork and Descemet's membrane as an additional treatment for intraocular pressure elevation after non-penetrating glaucoma surgery (NPGS), and its management.

Gonioscopy
Other Eye Conditions

This article provides a comprehensive explanation of gonioscopy: indications, techniques (static/dynamic/indentation), Shaffer/Scheie/Spaeth classifications, van Herick method, representative abnormal findings (PAS, neovascularization, angle recession, pediatric glaucoma), and comparison with imaging diagnostics.

Gonioscopy: Angle Imaging with a Gonioscope
Glaucoma

Explanation of indications, techniques, classification methods, and abnormal findings in gonioscopy. Details on direct and indirect methods, compression gonioscopy, comparison of Shaffer, Scheie, and Spaeth classifications, differentiation from AS-OCT and UBM, and the latest imaging devices.

Granular Corneal Dystrophy (GCD)
Cornea & External Eye

An autosomal dominant corneal dystrophy caused by TGFBI gene mutations, leading to deposition of hyaline and amyloid in the corneal stroma. It is classified into type 1 (R555W) and type 2 (R124H, formerly Avellino), with type 2 being overwhelmingly more common in Japan. PTK is the first-line treatment.

Granulomatosis with Polyangiitis
Uveitis

Granulomatosis with polyangiitis (GPA) is an ANCA-associated vasculitis characterized by necrotizing granulomatous vasculitis of small to medium vessels. It can affect almost all ocular tissues, including the orbit, sclera, and cornea, and also involves the upper respiratory tract, lungs, and kidneys.

Gyrate atrophy
Retina & Vitreous

Gyrate atrophy is an autosomal recessive retinal dystrophy caused by deficiency of ornithine aminotransferase due to OAT gene mutation, leading to highly elevated plasma ornithine and progressive atrophy of the choroid and retina. Responsiveness to vitamin B6 influences treatment strategy.