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Cataract & Anterior Segment

Toric Intraocular Lenses (Toric IOLs)

1. What Are Toric Intraocular Lenses (Toric IOLs)?

Section titled “1. What Are Toric Intraocular Lenses (Toric IOLs)?”

Toric IOLs are intraocular lenses (IOLs) used to simultaneously correct corneal astigmatism during cataract surgery. Astigmatism-correcting IOLs have a structure that adds cylindrical power to conventional IOLs to correct corneal astigmatism. The surgeon uses a calculator on the manufacturer’s website to determine the appropriate model, power, axis of fixation, and incision location for the specific case. At the end of surgery, the weak meridian of the IOL is aligned with the steep meridian of the cornea.

Cataract surgery is no longer just lens removal; it increasingly incorporates refractive correction. As patients increasingly desire spectacle-free lives after surgery, the importance of astigmatism correction continues to grow.

The first toric IOL was conceived in 1992 by Shimizu of Japan. It was a three-piece open-loop design made of PMMA with polypropylene haptics 2). Early silicone plate-haptic IOLs (Staar Surgical) had rotational stability issues, with 24% of early cases reporting rotation of 30 degrees or more 2). In 2006, Alcon launched the single-piece open-loop hydrophobic acrylic toric IOL (AcrySof), which became widely adopted due to its excellent rotational stability and reduced posterior capsule opacification (PCO) 2).

Corneal astigmatism of 1.0 D or more is present in approximately 30–40% of cataract outpatients, and 1.5 D or more is found in 15–29%. Uncorrected astigmatism is a major cause of reduced postoperative uncorrected visual acuity. Currently, regular astigmatism with cataract is the main indication, but it is also used in various conditions such as mild to moderate keratoconus, post-keratoplasty, and post-pterygium excision 2).

Insurance system: Toric IOLs are elective medical treatment (patient pays the difference). Only the difference from a monofocal IOL is borne by the patient; the cataract surgery itself is covered by health insurance.

Q What is a toric IOL?
A

It is a special intraocular lens that can simultaneously correct corneal astigmatism during cataract surgery. With a standard spherical IOL, astigmatism remains postoperatively, requiring glasses, but using a toric IOL allows many patients to be spectacle-free for distance vision. High success rates are achieved with appropriate patient selection, IOL calculation, and surgical technique. Monofocal toric IOLs are elective medical treatment (patient pays the difference), while the cataract surgery itself is covered by insurance.

The main subjective symptoms of astigmatism requiring a toric IOL are listed below.

  • Reduced distance vision: Especially worsens in low-light conditions
  • Blurred or distorted images: Characteristic reduction in vision in vertical or oblique directions
  • Dependence on glasses: Difficulty living without corrective glasses
  • Photophobia (glare): High astigmatism increases optical aberrations

The degree of visual impairment due to astigmatism depends not only on the power but also on the axis direction (with-the-rule, against-the-rule, oblique) 1). Against-the-rule (ATR) astigmatism is considered to have a greater impact on vision than with-the-rule (WTR) 1).

ExaminationKey findings
Manual refractionDetermine refractive astigmatism with careful examination
KeratometerCheck amount and axis of anterior segment astigmatism
Corneal topography/tomographyEssential to rule out irregular astigmatism5)
Optical biometerSimultaneously measures axial length and anterior chamber depth

Confirm that the direction and magnitude of astigmatism are consistent across all measurements. Discrepancies between measurements suggest irregular astigmatism or measurement error.

3. Causes and Risk Factors (Patient Selection Criteria)

Section titled “3. Causes and Risk Factors (Patient Selection Criteria)”

Good indication (indicated)

Corneal regular astigmatism: Regular astigmatism is required

Astigmatism amount: Usually 1.0 D or more (recommended by ESCRS; strong evidence for 2.0 D or more) 5)

Expectations: Realistic expectation of being free from distance glasses

Corneal stability: Stable measurements

Relative contraindications / Cases requiring caution

Irregular astigmatism: Unsuitable for corneal scars or corneal ectasia

Zonular weakness: High risk of rotation

Poor pupil dilation: Increases surgical difficulty

History of vitreoretinal or glaucoma surgery: May alter expected outcomes

The ESCRS guidelines (2024) recommend the use of toric IOLs for regular astigmatism of 1.0 D or more, with strong evidence (GRADE++) for 2.0 D or more and moderate evidence for 1.5 D or more 5). For astigmatism of 0.75 D or less, opposite clear corneal incision (OCCI) or adjustment of the main incision position is recommended as an alternative 5). Corneal relaxing incisions (LRI) carry a higher risk of residual astigmatism than toric IOLs 11).

Importance of posterior corneal astigmatism (PCA)

Section titled “Importance of posterior corneal astigmatism (PCA)”

Posterior corneal astigmatism (PCA) has long been overlooked, but it is now recognized as essential to incorporate into calculations 1)2).

Koch et al. (2012) reported a mean PCA of 0.30 D in 435 patients 2). It was also shown that the steep meridian of the posterior cornea is vertically oriented in 87% of patients 2). In with-the-rule (WTR) eyes, PCA reduces anterior corneal astigmatism, while in against-the-rule (ATR) eyes, it enhances it 1).

Calculation methods that incorporate PCA and effective lens position (ELP) may reduce postoperative residual astigmatism compared to those that do not 8). The ESCRS guidelines recommend that toric IOL calculators using measured PCA are potentially superior to predicted PCA in eyes with high PCA 5). The Barrett formula, Goggin Nomogram, and Baylor Nomogram incorporate this correction 1).

Preoperative evaluation before toric IOL implantation requires the following in addition to standard cataract surgery evaluation 5).

  1. Corneal topography/tomography: Determine the type, axis, and magnitude of astigmatism and rule out irregular astigmatism. ESCRS guidelines recommend it as mandatory for toric IOL planning (GRADE+) 5)
  2. Measurement or estimation of posterior corneal astigmatism: Scheimpflug devices (e.g., Pentacam) and anterior segment OCT are useful
  3. Manual refraction: Check for discrepancies between refractive astigmatism and corneal astigmatism
  4. Optical biometry: Measure axial length, anterior chamber depth, and effective lens position (ELP)

Perform multiple measurements and adopt stable values with little variation. Preoperative subjective refractive astigmatism is irrelevant for IOL planning (because lens-induced astigmatism disappears after surgery) 6).

Use the online toric calculator provided by each manufacturer. Input items include corneal astigmatism (cylinder power and axis), surgically induced astigmatism (SIA), axial length, anterior chamber depth, and desired incision location.

Representative calculation tools:

Recommended formula: New-generation formulas (Barrett Universal II, Kane, Hill-RBF, EVO, etc.) are recommended over traditional formulas due to lower trend errors (GRADE+) 5). Calculation methods that include posterior corneal astigmatism and effective lens position (ELP) are recommended, and using these calculations significantly reduces postoperative residual astigmatism 8).

Intraoperative aberrometry: Using intraoperative aberrometers such as ORA or Holos IntraOp enables real-time refraction measurement in the aphakic eye and assists in the alignment accuracy of toric IOLs 6). However, aberrometry does not always improve outcomes 6).

Q What should be considered when calculating toric IOL power?
A

The most important consideration is posterior corneal astigmatism (PCA). Many traditional calculation tools use only anterior corneal data; ignoring PCA can lead to overcorrection in with-the-rule astigmatism and undercorrection in against-the-rule astigmatism. Currently, it is recommended to use tools that incorporate PCA, such as the Barrett formula or the ESCRS calculator. Surgically induced astigmatism (SIA) must also be reflected using vector calculations. In long axial length eyes, the capsular bag is larger and the IOL is more prone to rotation, so this should be accounted for preoperatively.

Monofocal toric IOLs are primarily intended for distance vision correction. Glasses are needed for near and intermediate vision.

IOL NameMaterialCylinder Power (IOL Plane)Features
AcrySof IQ Toric / Clareon Toric (Alcon)Hydrophobic acrylic1.5–6.0 DOptic diameter 6 mm, 2.2 mm incision insertion. Most widely used.
TECNIS Toric (J&J Vision)Hydrophobic acrylic1.5 to 6.0 DWavefront design
enVista Toric (B+L)Hydrophobic acrylic1.25 to 5.75 DAberration-free design
Staar ToricSilicone2.0, 3.5 DPlate-type. Rotational stability is a concern.

Multifocal/EDOF toric IOLs provide simultaneous correction of astigmatism and near-to-distance vision. Representative examples include PanOptix Toric (Alcon), Vivity Toric (Alcon), and TECNIS Symfony Toric (J&J Vision). Toric multifocal IOLs offer better predictability and rotational stability than spherical multifocal IOLs combined with corneal relaxing incisions 6).

Step 1: Preoperative marking (axis identification)

Place the patient in a sitting (or standing) position and have them look straight ahead while marking the corneal limbus with reference marks. Since cyclotorsion occurs when lying down, this must be done in the sitting position 1). It is important to identify the axis before anesthesia 1).

Marking methods:

  • Manual marking method: Use a slit lamp microscope to directly mark positions such as 3, 6, and 9 o’clock.
  • Image-guided system: CALLISTO eye (Zeiss) and VERION (Alcon) recognize iris texture and conjunctival vessels to automatically identify the axis. They also compensate for cyclotorsion in the supine position. A meta-analysis by Zhou et al. (2019) in the ESCRS guidelines found that image-guided marking results in significantly less axis misalignment compared to manual marking (weighted mean difference −1.33°) and slightly less postoperative residual astigmatism (WMD −0.14D) (GRADE+) 5)9).

Step 2: IOL insertion and axis alignment

After injecting ophthalmic viscosurgical device (OVD), roughly position the IOL about 10–15 degrees before the final target position (counterclockwise). Carefully remove the OVD, then rotate the IOL to the target position, aligning the IOL’s weak meridian mark with the corneal steep meridian.

Postoperative follow-up:

  • Perform examinations at 1 day, 1 week, and 1 month after surgery, similar to routine cataract surgery.
  • If the IOL axis position and refraction results do not match, suspect IOL rotation.
  • Axis correction surgery (IOL rotation) at 2–4 weeks postoperatively is the appropriate timing 1)
  • Correction in the late phase (several months later) after capsular contraction has progressed may be technically difficult 1)
Q What should be done if astigmatism remains after surgery?
A

First, confirm the IOL axis position and postoperative refraction. If axis misalignment is the cause, perform reoperation (repositioning) to rotate the IOL to the correct position, aiming for 2–4 weeks postoperatively. If the IOL cylinder power is inappropriate, IOL exchange or additional surgery is required. If a non-toric IOL was used, options include supplementary toric IOL insertion in the ciliary sulcus or corneal laser enhancement (LASIK, PRK, etc.).

Relationship between Astigmatism and Visual Acuity

Section titled “Relationship between Astigmatism and Visual Acuity”

Uncorrected astigmatism reduces visual acuity 1). The effect depends not only on the power but also on the axis direction; against-the-rule astigmatism has a greater impact on visual acuity than with-the-rule astigmatism 1). Since removal of the crystalline lens during cataract surgery eliminates the lenticular astigmatic component, postoperative astigmatism is essentially only corneal astigmatism (anterior + posterior) 6).

A toric IOL has cylinder power on the lens. The lowest power toric IOL is typically 1.0 D (at the IOL plane), which corresponds to correction of 0.5–0.6 D of corneal astigmatism 1). The required cylinder power may change when the spherical power of the IOL changes, and the effective lens position also affects the correction amount 1).

The cataract surgery incision itself induces mild astigmatism (approximately 0.3–0.5 D with small incision surgery). For toric IOL power calculation, the residual astigmatism after subtracting SIA is used. SIA is a multifactorial factor depending on incision location, size, and surgeon experience 5).

  • IOL material: Hydrophobic acrylic has higher adhesion to the posterior capsule than hydrophilic acrylic or silicone, providing superior rotational stability 1)
  • Capsular bag size: In eyes with long axial length and large capsular bag (high myopia), contact between the IOL and the bag wall is reduced, making rotation more likely 1)
  • Removal of ophthalmic viscosurgical device: Residual material can cause the IOL to slide within the capsular bag
  • CCC shape and size: When the CCC covers the entire circumference of the IOL optic, it contributes to both rotational stability and prevention of posterior capsule opacification6)
  • Timing of rotation: Often occurs early, from 1 hour to the day after surgery

7. Latest research and future perspectives

Section titled “7. Latest research and future perspectives”

In an evidence-based review by Goggin (2022), the following outcomes are achievable with appropriate preoperative planning, calculation, and surgical technique1):

  • Alignment accuracy: Within 5 degrees of the intended axis is achieved in routine cases
  • Postoperative residual astigmatism: An average of approximately 0.4 D is achievable
  • Achievement rate: Approximately 100% within 1 D of target, approximately 90% within 0.5 D

In a meta-analysis by Kessel et al. (2016) (13 studies), toric IOLs significantly improved UDVA compared to non-toric IOLs (logMAR MD −0.07 to −0.10), and the rate of spectacle independence for distance was significantly higher (RR 0.51, 95% CI 0.36–0.71)7).

When residual astigmatism remains after insertion of an existing non-toric IOL, an additional toric IOL can be placed in the ciliary sulcus (STIOL) as an option3).

In a systematic review by Rocha-de-Lossada et al. (2023) (155 eyes)3):

  • 57.41% of eyes achieved target astigmatism within ±0.50 D
  • Mean rotation: 30.48 ± 19.90 degrees (rotational stability remains a challenge)
  • 32.25% of cases required repositioning surgery
  • Complications: ocular hypertension 1.93%, corneal edema 1.29%, corneal degeneration 1.29%, pigment dispersion 0.64%

Expanded Indications: Toric IOL for Keratoconus

Section titled “Expanded Indications: Toric IOL for Keratoconus”

In cataract surgery for patients with keratoconus (KC), irregular anterior-posterior corneal curvature ratio, non-orthogonality of axes, and errors in ELP estimation can cause reduced accuracy 4). Systematic reviews and meta-analyses report that relatively satisfactory postoperative outcomes can be achieved in mild to moderate keratoconus, but in advanced keratoconus, the rate of achieving within 1 D of target is only 12–48% 4). The ESCRS guidelines recommend using the Barrett True-K and Kane keratoconus formulas for keratoconus and advise against conventional formulas (e.g., SRK/T) (GRADE+) 5).

  • Light Adjustable Lens (LAL): A technology that allows fine-tuning of spherical and cylindrical power postoperatively by moving unpolymerized photosensitive silicone macromers with ultraviolet irradiation 6)
  • Refractive Index Shaping with Femtosecond Laser: A technology that enables postoperative modification of power, cylinder, and number of foci by femtosecond laser treatment of acrylic IOLs 6)
  • Digital Marking and AI Integration: Further improvement of alignment accuracy through seamless integration of preoperative data and intraoperative images
Q Can toric IOLs be used even with keratoconus?
A

In mild to moderate stable keratoconus, toric IOLs may be useful. However, irregular corneal shape reduces the predictive accuracy of astigmatism correction. Systematic reviews report relatively good outcomes in mild to moderate cases (Krumeich I–II), but in advanced keratoconus, the rate of achieving within 1 D of target tends to be low. The ESCRS guidelines recommend using the Kane keratoconus adjusted formula or Barrett True-K.

  1. Goggin M. Toric intraocular lenses: Evidence-based use. Clin Experiment Ophthalmol. 2022;50(5):481-489.
  2. Singh VM, Ramappa M, Murthy SI, Rostov AT. Toric intraocular lenses: Expanding indications and preoperative and surgical considerations to improve outcomes. Indian J Ophthalmol. 2022;70(1):10-23.
  3. Rocha-de-Lossada C, García-Lorente M, Zamora-de La Cruz D, et al. Supplemental Toric Intraocular Lenses in the Ciliary Sulcus for Correction of Residual Refractive Astigmatism: A Review. Ophthalmol Ther. 2023;12(4):1813-1826.
  4. Yahalomi T, Achiron A, Hecht I, et al. Refractive Outcomes of Non-Toric and Toric Intraocular Lenses in Mild, Moderate and Advanced Keratoconus: A Systematic Review and Meta-Analysis. J Clin Med. 2022;11(9):2456.
  5. European Society of Cataract and Refractive Surgeons (ESCRS). ESCRS Guideline for Cataract Surgery. Dublin: ESCRS; 2024.
  6. American Academy of Ophthalmology. Cataract in the Adult Eye Preferred Practice Pattern. San Francisco: AAO; 2021.
  7. Kessel L, Andresen J, Tendal B, et al. Toric intraocular lenses in the correction of astigmatism during cataract surgery: a systematic review and meta-analysis. Ophthalmology. 2016;123(2):275-286. doi:10.1016/j.ophtha.2015.10.002. PMID: 26601819.
  8. Yeu E, Cheung AY, Potvin R. Clinical outcomes of toric intraocular lenses: differences in expected outcomes when using a calculator that considers effective lens position and the posterior cornea vs one that does not. Clin Ophthalmol. 2020;14:815-822. doi:10.2147/OPTH.S247800.
  9. Zhou F, Jiang W, Lin Z, et al. Comparative meta-analysis of toric intraocular lens alignment accuracy in cataract patients: image-guided system versus manual marking. J Cataract Refract Surg. 2019;45(9):1340-1345.
  10. Potvin R, Kramer BA, Hardten DR, Berdahl JP. Toric intraocular lens orientation and residual refractive astigmatism: an analysis. Clin Ophthalmol. 2016;10:1829-1836.
  11. Nanavaty MA, Bedi KK, Ali S, et al. Toric intraocular lenses versus peripheral corneal relaxing incisions for astigmatism between 0.75 and 2.5 diopters during cataract surgery. Am J Ophthalmol. 2017;180:165-177.

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