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Cataract & Anterior Segment

Toric Intraocular Lenses (Toric IOLs)

1. What Are Toric Intraocular Lenses (Toric IOLs)?

Section titled “1. What Are Toric Intraocular Lenses (Toric IOLs)?”

A toric IOL is an intraocular lens (IOL) used to simultaneously correct corneal astigmatism during cataract surgery. Astigmatism-correcting IOLs have a structure that adds cylindrical power to conventional IOLs to correct corneal astigmatism. The surgeon uses a calculator on the manufacturer’s website to determine the appropriate astigmatism-correcting IOL model, power, fixation axis, and incision location for the specific case. At the end of surgery, the weak meridian of the IOL is aligned with the steep meridian of the cornea.

Cataract surgery is no longer merely lens removal; its role as a refractive surgery is increasingly emphasized. As patients increasingly desire spectacle-free lives after surgery, the importance of astigmatism correction continues to grow.

The first toric IOL was conceived in 1992 by Shimizu in Japan. It was a three-piece open-loop design made of PMMA with polypropylene haptics 2). Early silicone plate-haptic IOLs (Staar Surgical) had rotational stability issues, with 24% of early cases reporting rotation of 30 degrees or more 2). In 2006, Alcon launched a single-piece open-loop hydrophobic acrylic toric IOL (AcrySof), which became widely adopted due to excellent rotational stability and reduced posterior capsule opacification (PCO) 2).

Corneal astigmatism of 1.0 D or more is present in approximately 30–40% of cataract outpatients, and 1.5 D or more is found in 15–29%. Uncorrected astigmatism is a major cause of reduced postoperative uncorrected visual acuity. Currently, regular astigmatism with cataracts is the main indication, but it is also used in various conditions such as mild to moderate keratoconus, post-keratoplasty, and post-pterygium excision 2).

Insurance system: Toric IOLs are covered under selected medical treatment (patient pays the difference). Only the difference from a monofocal IOL is borne by the patient, while the cataract surgery itself is covered by health insurance.

Q What is a toric IOL?
A

It is a special intraocular lens that can simultaneously correct corneal astigmatism during cataract surgery. With a standard spherical IOL, astigmatism remains after surgery, requiring glasses, but using a toric IOL allows many patients to be free from glasses for distance vision. High success rates are achieved through appropriate patient selection, IOL calculation, and surgical technique. Monofocal toric IOLs are selected medical treatment (patient pays the difference), while the cataract surgery itself is covered by insurance.

The main subjective symptoms of astigmatism requiring a toric IOL are listed below.

  • Decreased distance vision: Worsens especially in low-light conditions
  • Blurred or distorted images: Characteristic decrease in vision in vertical or oblique directions
  • Dependence on glasses: Difficulty in daily life without corrective glasses
  • Photophobia (glare): Higher astigmatic power increases optical aberrations

The degree of visual impairment due to astigmatism depends not only on the power but also on the axis (with-the-rule, against-the-rule, oblique) 1). Against-the-rule (ATR) astigmatism is considered to have a greater impact on vision than with-the-rule (WTR) astigmatism 1).

ExaminationKey findings
Manual refractionDetermine refractive astigmatism with careful examination
KeratometerCheck the amount and axis of anterior segment astigmatism
Corneal topography/tomographyEssential for excluding irregular astigmatism5)
Optical biometerSimultaneously measures axial length and anterior chamber depth

Confirm that the direction and magnitude of astigmatism are consistent across all measurements. Discrepancies between measurements suggest irregular astigmatism or measurement error.

3. Causes and risk factors (patient selection criteria)

Section titled “3. Causes and risk factors (patient selection criteria)”

Good indications (appropriate)

Corneal regular astigmatism: Regular astigmatism is required

Astigmatism amount: Typically 1.0 D or more. For 2.0 D or more, the evidence is relatively strong5)

Expectations: Realistic expectations for spectacle independence for distance

Corneal stability: Stable measurements

Relative contraindications and cautionary cases

Irregular astigmatism: Not suitable for corneal scars or corneal ectasia

Zonular weakness: High risk of rotation

Poor pupil dilation: Increases surgical difficulty

History of vitreoretinal or glaucoma surgery: May alter expected outcomes

For regular astigmatism of 1.0 D or more, a toric IOL is a useful option, and for 2.0 D or more, the evidence is particularly strong5). For astigmatism of 0.75 D or less, alternative methods such as opposite clear corneal incision (OCCI) or adjustment of the main incision position are available5). Corneal relaxing incisions (LRI) carry a higher risk of residual astigmatism than toric IOLs11).

Importance of posterior corneal astigmatism (PCA)

Section titled “Importance of posterior corneal astigmatism (PCA)”

Posterior corneal astigmatism (PCA) has long been overlooked, but it is now recognized as essential to incorporate into calculations1)2).

Koch et al. (2012) reported a mean PCA of 0.30 D in 435 patients2). It was also shown that the steep meridian of the posterior cornea is vertically oriented in 87% of patients2). In with-the-rule (WTR) eyes, PCA reduces anterior corneal astigmatism, while in against-the-rule (ATR) eyes, it enhances it1).

Calculation methods incorporating PCA and ELP may reduce postoperative residual astigmatism compared to those that do not consider them8). In eyes with high PCA, toric IOL calculators using measured PCA are potentially superior to those using predicted PCA5). The Barrett formula, Goggin Nomogram, and Baylor Nomogram incorporate this correction1).

Preoperative evaluation before toric IOL implantation requires the following in addition to standard cataract surgery evaluation5).

  1. Corneal topography/tomography: Determines the type, axis, and magnitude of astigmatism and excludes irregular astigmatism. This is an essential examination when planning toric IOLs5)
  2. Measurement or estimation of posterior corneal astigmatism: Scheimpflug devices (e.g., Pentacam) and anterior segment OCT are useful
  3. Manual refraction: Confirms no discrepancy between refractive astigmatism and corneal astigmatism
  4. Optical biometry: Measures axial length, anterior chamber depth, and effective lens position (ELP)

Multiple measurements are taken, and stable values with little variation are adopted. Preoperative subjective refractive astigmatism is irrelevant for IOL planning (because lenticular astigmatism disappears with surgery)6).

Calculation of IOL Power and Cylinder Power

Section titled “Calculation of IOL Power and Cylinder Power”

Use the online toric calculator provided by each manufacturer. Input items include corneal astigmatism (cylinder power and axis), surgically induced astigmatism (SIA), axial length, anterior chamber depth, and desired incision location.

Representative calculation tools:

Recommended formula: New-generation formulas (Barrett Universal II, Kane, Hill-RBF, EVO, etc.) have fewer trend errors than conventional formulas and are recommended5). Calculation methods that include posterior corneal astigmatism and ELP are recommended, and calculations that account for these significantly reduce postoperative residual astigmatism8).

Intraoperative aberrometry: Using intraoperative aberrometers such as ORA or Holos IntraOp enables real-time refraction measurement in the aphakic eye and assists in the accuracy of toric IOL alignment6). However, aberrometry does not always improve outcomes6).

Q What should be noted when calculating toric IOL power?
A

The most important consideration is posterior corneal astigmatism (PCA). Many conventional calculation tools use only anterior corneal data, and ignoring PCA can lead to overcorrection in with-the-rule astigmatism and undercorrection in against-the-rule astigmatism. Currently, it is recommended to use tools such as the Barrett formula or the ESCRS calculator that incorporate PCA. Surgically induced astigmatism (SIA) must also be reflected using vector calculations. In eyes with long axial length, the capsular bag is large and the IOL is prone to rotation, so this should be accounted for preoperatively.

Monofocal toric IOLs are primarily intended for distance vision correction. Glasses are needed for near and intermediate vision.

IOL NameMaterialCylinder Power (IOL Plane)Features
AcrySof IQ Toric / Clareon Toric (Alcon)Hydrophobic acrylic1.5–6.0 DOptic diameter 6 mm, 2.2 mm incision insertion. Most widely used.
TECNIS Toric (J&J Vision)Hydrophobic acrylic1.5–6.0 DWavefront design
enVista Toric (B+L)Hydrophobic acrylic1.25–5.75 DAberration-free design
Staar ToricSilicone2.0, 3.5 DPlate-type. Rotational stability is a concern

Multifocal/EDOF toric IOLs provide simultaneous correction of astigmatism and near-to-distance vision. Representative examples include PanOptix Toric (Alcon), Vivity Toric (Alcon), and TECNIS Symfony Toric (J&J Vision). Compared to spherical multifocal IOLs with corneal relaxing incisions, toric multifocal IOLs offer better predictability and rotational stability6).

Step 1: Preoperative marking (axis identification)

Place the patient in a sitting (or standing) position, have them look straight ahead, and mark the corneal limbus with a reference mark. Since ocular cyclotorsion occurs when lying down, this must be done in the sitting position 1). It is important to identify the axis before anesthesia 1).

Marking methods:

  • Manual marking method: Use a slit lamp microscope to directly mark positions such as 3, 6, and 9 o’clock.
  • Image-guided system: CALLISTO eye (Zeiss) and VERION (Alcon) automatically identify the axis by recognizing iris texture and conjunctival vessels. They also compensate for ocular cyclotorsion in the supine position. A meta-analysis of ESCRS guidelines (Zhou et al. 2019) showed that image-guided marking results in significantly smaller axis deviation (weighted mean difference −1.33°) and slightly less postoperative residual astigmatism (WMD −0.14D) compared to manual marking 5)9).

Step 2: IOL insertion and alignment

After injecting ophthalmic viscosurgical device (OVD), roughly position the IOL about 10 to 15 degrees before the final target position (counterclockwise). Carefully remove the OVD, then rotate the IOL to the target position, aligning the IOL’s weak meridian mark with the cornea’s steep meridian.

Postoperative follow-up:

  • Examine the patient at 1 day, 1 week, and 1 month postoperatively, as in standard cataract surgery.
  • If the IOL axis position and refraction results do not match, suspect IOL rotation.
  • Axis correction surgery (IOL rotation) is appropriate at 2–4 weeks postoperatively 1)
  • Correction in the late phase (several months later) after capsular contraction has progressed may be technically difficult 1)
Q What should be done if astigmatism remains after surgery?
A

First, confirm the IOL axis position and postoperative refraction. If axis misalignment is the cause, perform repositioning surgery to rotate the IOL to the correct position, ideally at 2–4 weeks postoperatively. If the IOL cylinder power is inappropriate, IOL exchange or additional surgery may be needed. If a non-toric IOL was used, options include supplementary toric IOL insertion in the ciliary sulcus or enhancement with corneal laser (LASIK, PRK, etc.).

6. Pathophysiology and Detailed Mechanisms

Section titled “6. Pathophysiology and Detailed Mechanisms”

Relationship Between Astigmatism and Visual Acuity

Section titled “Relationship Between Astigmatism and Visual Acuity”

Uncorrected astigmatism reduces visual acuity 1). The effect depends not only on the power but also on the axis; against-the-rule astigmatism has a greater impact on visual acuity than with-the-rule astigmatism 1). Since removal of the crystalline lens during cataract surgery eliminates the lenticular astigmatic component, postoperative astigmatism is essentially only corneal astigmatism (anterior + posterior) 6).

A toric IOL has cylinder power on the lens. The lowest-power toric IOL is typically 1.0 D (at the IOL plane), which corresponds to correcting 0.5–0.6 D of corneal astigmatism 1). Changes in the IOL spherical power may alter the required cylinder power, and the effective lens position also affects the correction amount 1).

The cataract surgery incision itself induces mild astigmatism (approximately 0.3–0.5 D with small-incision surgery). Toric IOL power calculation uses the residual astigmatism after subtracting SIA. SIA is a multifactorial factor depending on incision location, size, and surgeon experience 5).

  • IOL material: Hydrophobic acrylic has better adhesion to the posterior capsule than hydrophilic acrylic or silicone, offering superior rotational stability 1)
  • Capsular bag size: In eyes with a long axial length and large capsular bag (high myopia), contact between the IOL and the bag wall is reduced, making rotation more likely 1)
  • Removal of ophthalmic viscosurgical device: Residual OVD can cause the IOL to slide within the capsular bag
  • CCC shape and size: A CCC that covers the entire circumference of the IOL optic contributes to both rotational stability and prevention of posterior capsule opacification6)
  • Timing of rotation: Often occurs early, from 1 hour to the next day after surgery

7. Latest Research and Future Perspectives

Section titled “7. Latest Research and Future Perspectives”

An evidence-based review by Goggin (2022) indicates that with appropriate preoperative planning, calculation, and surgical technique, the following outcomes can be achieved1):

  • Alignment accuracy: Within 5 degrees of the intended axis in routine cases
  • Postoperative residual astigmatism: Average of approximately 0.4 D achievable
  • Achievement rate: Approximately 100% within 1 D and 90% within 0.5 D of target

A meta-analysis by Kessel et al. (2016) of 13 studies found that toric IOLs significantly improved uncorrected distance visual acuity (UDVA) compared to non-toric IOLs (logMAR MD −0.07 to −0.10) and significantly reduced the need for distance spectacles (RR 0.51, 95% CI 0.36–0.71)7).

When residual astigmatism remains after insertion of an existing non-toric IOL, an additional toric IOL can be placed in the ciliary sulcus (STIOL) as an option3).

A systematic review by Rocha-de-Lossada et al. (2023) of 155 eyes reported3):

  • 57.41% of eyes achieved target astigmatism within ±0.50 D
  • Mean rotation: 30.48 ± 19.90 degrees (rotational stability remains a challenge)
  • 32.25% of cases required repositioning surgery
  • Complications: ocular hypertension 1.93%, corneal edema 1.29%, corneal degeneration 1.29%, pigment dispersion 0.64%

Expanded indications: toric IOL for keratoconus

Section titled “Expanded indications: toric IOL for keratoconus”

In cataract surgery for keratoconus (KC) patients, factors such as irregular anterior-posterior corneal curvature ratio, non-orthogonal axes, and errors in ELP estimation can reduce accuracy 4). Systematic reviews and meta-analyses report that relatively satisfactory postoperative outcomes can be achieved in mild to moderate keratoconus, but in advanced keratoconus, the rate of achieving within 1 D of the target is only 12–48% 4). For keratoconus, use the Barrett True-K or Kane keratoconus formula, and handle conventional formulas (e.g., SRK/T) with caution 5).

  • Light Adjustable Lens (LAL): A technology that allows fine-tuning of spherical and cylindrical power postoperatively by moving unpolymerized photosensitive silicone macromers with ultraviolet irradiation 6)
  • Refractive Index Shaping with femtosecond laser: A technology that enables postoperative modification of power, cylinder, and focal points by femtosecond laser treatment of acrylic IOLs 6)
  • Digital marking and AI integration: Further improvement of alignment accuracy through seamless integration of preoperative data and intraoperative images
Q Can toric IOLs be used even with keratoconus?
A

For mild to moderate stable keratoconus, toric IOLs may be useful. However, due to irregular corneal shape, the predictive accuracy of astigmatism correction is reduced. Systematic reviews report relatively good outcomes in mild to moderate cases (Krumeich grade I–II), but in advanced keratoconus, the rate of achieving within 1 D of the target tends to be low. Consider using the Kane keratoconus adjusted formula or Barrett True-K for calculations.

  1. Goggin M. Toric intraocular lenses: Evidence-based use. Clinical & experimental ophthalmology. 2022;50(5):481-489. doi:10.1111/ceo.14106. PMID:35584257; PMCID:PMC9543206.
  2. Singh VM, Ramappa M, Murthy SI, Rostov AT. Toric intraocular lenses: Expanding indications and preoperative and surgical considerations to improve outcomes. Indian journal of ophthalmology. 2022;70(1):10-23. doi:10.4103/ijo.IJO_1785_21. PMID:34937203; PMCID:PMC8917572.
  3. Rocha-de-Lossada C, García-Lorente M, La Cruz DZ, Rodríguez-Calvo-de-Mora M, Fernández J. Supplemental Toric Intraocular Lenses in the Ciliary Sulcus for Correction of Residual Refractive Astigmatism: A Review. Ophthalmology and therapy. 2023;12(4):1813-1826. doi:10.1007/s40123-023-00721-0. PMID:37145259; PMCID:PMC10287861.
  4. Yahalomi T, Achiron A, Hecht I, Arnon R, Levinger E, Pikkel J, et al. Refractive Outcomes of Non-Toric and Toric Intraocular Lenses in Mild, Moderate and Advanced Keratoconus: A Systematic Review and Meta-Analysis. Journal of clinical medicine. 2022;11(9). doi:10.3390/jcm11092456. PMID:35566583; PMCID:PMC9101494.
  5. European Society of Cataract and Refractive Surgeons (ESCRS). ESCRS Guideline for Cataract Surgery. Dublin: ESCRS; 2024.
  6. Miller KM, Oetting TA, Tweeten JP, Carter K, Lee BS, Lin S, et al. Cataract in the Adult Eye Preferred Practice Pattern. Ophthalmology. 2022;129(1):P1-P126. doi:10.1016/j.ophtha.2021.10.006. PMID:34780842.
  7. Kessel L, Andresen J, Tendal B, et al. Toric intraocular lenses in the correction of astigmatism during cataract surgery: a systematic review and meta-analysis. Ophthalmology. 2016;123(2):275-286. doi:10.1016/j.ophtha.2015.10.002. PMID: 26601819.
  8. Yeu E, Cheung AY, Potvin R. Clinical outcomes of toric intraocular lenses: differences in expected outcomes when using a calculator that considers effective lens position and the posterior cornea vs one that does not. Clin Ophthalmol. 2020;14:815-822. doi:10.2147/OPTH.S247800.
  9. Zhou F, Jiang W, Lin Z, Li X, Li J, Lin H, et al. Comparative meta-analysis of toric intraocular lens alignment accuracy in cataract patients: Image-guided system versus manual marking. Journal of cataract and refractive surgery. 2019;45(9):1340-1345. doi:10.1016/j.jcrs.2019.03.030. PMID:31470944.
  10. Potvin R, Kramer BA, Hardten DR, Berdahl JP. Toric intraocular lens orientation and residual refractive astigmatism: an analysis. Clinical ophthalmology (Auckland, N.Z.). 2016;10:1829-1836. doi:10.2147/OPTH.S114118. PMID:27703323; PMCID:PMC5036610.
  11. Nanavaty MA, Bedi KK, Ali S, et al. Toric intraocular lenses versus peripheral corneal relaxing incisions for astigmatism between 0.75 and 2.5 diopters during cataract surgery. Am J Ophthalmol. 2017;180:165-177. doi:10.1016/j.ajo.2017.06.007.

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